Our team is constantly trying to improve Overwolf and make it silky smooth for you, we do have some known-issues of conflicting with the following programs so we wanted to let you know –
Alienware Sound Center
Asus Sonic Radar \ Sonic Suite (also AI Suite)
Recording with Overwolf while any of these programs are running as well, might cause sound issues and sometimes it might not even record at all. Our dev team is doing their best to find a permanent solution, but for now please make sure to disable these programs before you start recording with Overwolf.